Biostimulator Filler

Biosimulator Fillers

It’s a common misconception that your skin stretches over time, sagging into folds and wrinkles.

doctor injector

In reality, two primary factors age our appearance – loss of facial volume due to depletion of fat in the face and bone in the skull that support the skin and reduced production of collagen.

Natural volume gives our face smooth, youthful contours and we begin to lose both, beginning as early as our 20s, but usually in our late 20s- early 30s.

Collagen is a strong meshwork of protein fibers that supports the skin, forming the foundation for longlasting, radiant skin.

While hyaluronic acid based dermal fillers have an important use for replenishing depleted volume in the face immediately, it is possible to look overfilled, as we can see all around us, especially in lips and cheeks.

Biostimulator fillers work differently and are a newer brand of injectables that work over time to stimulate your own collagen production, that can often last as long as 18-24 months.

At Skin Essentials, we offer two main brands, which we are not allowed to name due to TGA regulations.

Biostimulator Filler 1

patient 3
patient 2
patient 1
  • In the market since 2004, this is an injectable form of the drug also used to make a brand of longer listing threads for threadlift and as seen in this article here from 2009 can be great for longlasting natural results in appropriately chosen patients.
  • Usually not for those in a hurry as patience is needed, usually 3 sessions over a month apart for best results and then maintenance thereafter every year or so as needed.
  • Evidence suggests it is currently the longest lasting filler on the market, with effects lasting 2 years and beyond.

Biostimulator Filler 2

Biostimulator Filler R patient 1
Biostimulator Filler R patient 2

Has been in the market since 2006, this one is slightly different in that it is a volumizing filler used to plump up moderate to severe facial wrinkles and to restore lost volume, such as the nasolabial folds and the cheeks. However, it is so much more than just a volumizing filler.

Unlike hyaluronic acid fillers this filler works by stimulating your body to produce collagen. It is made of Calcium Hydroxyapatite (CaHA) microspheres suspended in an aqueous gel carrier. When injected, it immediately adds volume to deficient areas and contours facial features. Over time, the gel is fully absorbed and the body uses up the CaHA microspheres (which are a component of collagen), leaving behind your own natural collagen.

It was first FDA approved in 2006 for treating folds and wrinkles in the face and in 2015, it also received FDA approval for treating volume loss in the back of the hands. To date, it is the only dermal filler approved for this purpose.

This filler provides an immediate lift by restoring lost volume in the treated areas, such as the cheeks and temples. It corrects deep facial folds such as the nasolabial lines and results continue to improve over the next 3 months. The skin becomes smoother and firmer when the CaHA particles stimulate collagen in your skin with associated tightening to pull the skin upwards and improve facial contours.

Lastly, this filler can be hyper-diluted and used primarily as a skin rejuvenator –when the procedure is performed this way, the skin rejuvenating effects are even more pronounced and visible – suitable for annual rejuvenation of sundamaged, worn areas such as the face, neck, decolletage and hands.

Read here for a comparison of the two types of biostimulator fillers.

How do you decide?


By booking in your consultation with Dr Joshi, for a face to face assessment of your concerns, your needs and then what the best options for you are.

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